Tesofensine is a triple monoamine reuptake inhibitor (MRI) that modulates dopaminergic, noradrenergic, and serotonergic neurotransmission. It selectively inhibits the presynaptic reuptake of dopamine (DA), norepinephrine (NE), and serotonin (5-HT), influencing neurotransmitter availability and receptor interactions.
This compound undergoes hepatic metabolism via cytochrome P450 enzymes (CYP3A4), producing active metabolites with prolonged systemic activity.
Properties
- Chemical Formula : C17H23Cl2NO
- Synonyms : NS-2330, UNII-BLH9UKX9V1, BLH9UKX9V1, ZINC3953158
- Molar Mass : 328.3 g/mol
- CAS Number : 195875-84-4
- PubChem : 11370864
- Total Amount of the Active Ingredient : 15mg (0.25mg per 1 capsule)
- Shelf Life : 36 months
Tesofensine is a triple monoamine reuptake inhibitor (MRI) that modulates dopaminergic, noradrenergic, and serotonergic neurotransmission. It selectively inhibits the presynaptic reuptake of dopamine (DA), norepinephrine (NE), and serotonin (5-HT), influencing neurotransmitter availability and receptor interactions.
This compound undergoes hepatic metabolism via cytochrome P450 enzymes (CYP3A4), producing active metabolites with prolonged systemic activity.
- Chemical Formula : C17H23Cl2NO
- Synonyms : NS-2330, UNII-BLH9UKX9V1, BLH9UKX9V1, ZINC3953158
- Molar Mass : 328.3 g/mol
- CAS Number : 195875-84-4
- PubChem : 11370864
- Total Amount of the Active Ingredient : 15mg (0.25mg per 1 capsule)
- Shelf Life : 36 months

















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